Blaauboer, Bas. J.: search on Z-Library

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1

Prediction of in vivo developmental toxicity of all-trans-retinoic acid based on in vitro toxicity data and in silico physiologically based kinetic modeling

Louisse, Jochem, Bosgra, Sieto, Blaauboer, Bas J., Rietjens, Ivonne M. C. M., Verwei, Miriam

Journal:

Archives of Toxicology

Year:

2015

Language:

english

File:

PDF, 805 KB

english, 2015

2

Stem Cell-Derived Systems in Toxicology Assessment

Suter-Dick, Laura, Alves, Paula M., Blaauboer, Bas J., Bremm, Klaus-Dieter, Brito, Catarina, Coecke, Sandra, Flick, Burkhard, Fowler, Paul, Hescheler, Jürgen, Ingelman-Sundberg, Magnus, Jennings, Paul

Journal:

Stem Cells and Development

Year:

2015

Language:

english

File:

PDF, 671 KB

english, 2015

3

Toxicodynamic modelling and the interpretation of in vitro toxicity data

Bas J Blaauboer

Journal:

Toxicology Letters

Year:

2001

Language:

english

File:

PDF, 168 KB

english, 2001

4

Considering new methodologies in strategies for safety assessment of foods and food ingredients

Blaauboer, Bas J., Boobis, Alan R., Bradford, Bobbie, Cockburn, Andrew, Constable, Anne, Daneshian, Mardas, Edwards, Gareth, Garthoff, Jossie A., Jeffery, Brett, Krul, Cyrille, Schuermans, Jeroen

Journal:

Food and Chemical Toxicology

Year:

2016

Language:

english

File:

PDF, 839 KB

english, 2016

5

Induction of terminal differentiation in cultured human keratinocytes by polychlorinated aromatic hydrocarbons as measured by cell size analysis

Frank N.A.M. Van Pelt, Ine G.A.M. Hassing, Marion A. Stelling, Willem Seinen, Bas J. Blaauboer

Journal:

Toxicology and Applied Pharmacology

Year:

1992

Language:

english

File:

PDF, 840 KB

english, 1992

6

Toward in vitro biomarkers for developmental toxicity and their extrapolation to the in vivo situation

Louisse, Jochem, Verwei, Miriam, Woutersen, Ruud A, Blaauboer, Bas J, Rietjens, Ivonne MCM

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2012

Language:

english

File:

PDF, 653 KB

english, 2012

7

Editorial

Dan Acosta, Bas J. Blaauboer

Journal:

Toxicology in Vitro

Year:

1995

Language:

english

File:

PDF, 80 KB

english, 1995

8

An in vitro test strategy for predicting human acute toxicity

Bas J. Blaauboer

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

9

Theme B: The Validation and Regulatory Acceptance of Alternative Test Methods

Blaauboer, Bas J.

Journal:

Journal of Applied Animal Welfare Science

Year:

2000

Language:

english

File:

PDF, 115 KB

english, 2000

10

Biokinetic and Toxicodynamic Modelling and its Role in Toxicological Research and Risk Assessment

Blaauboer, Bas J.

Journal:

Alternatives to laboratory animals : ATLA

Year:

2003

Language:

english

File:

PDF, 78 KB

english, 2003

11

Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity. How to evaluate the risk of the S-EDCs?

Autrup, Herman, Barile, Frank A., Berry, Sir Colin, Blaauboer, Bas J., Boobis, Alan, Bolt, Herrmann, Borgert, Christopher J., Dekant, Wolfgang, Dietrich, Daniel, Domingo, Jose L., Gori, Gio Batta, Gre

Journal:

Toxicology Letters

Year:

2020

File:

PDF, 456 KB

2020

12

Proceedings of the 17th ESTIV congress 2012

Vinken, Mathieu, Scarino, Maria Laura, Roggen, Erwin, Blaauboer, Bas J.

Journal:

Toxicology in Vitro

Year:

2014

Language:

english

File:

PDF, 183 KB

english, 2014

13

Preface

Reinhardt, Christoph A., Blaauboer, Bas J.

Journal:

Toxicology in Vitro

Year:

1991

Language:

english

File:

PDF, 87 KB

english, 1991

14

Biokinetic Modeling and in Vitro – in Vivo Extrapolations

Blaauboer, Bas J.

Journal:

Journal of Toxicology and Environmental Health Part B

Year:

2010

Language:

english

File:

PDF, 198 KB

english, 2010

15

The Necessity of Biokinetic Information in the Interpretation of In Vitro Toxicity Data

Blaauboer, Bas J.

Journal:

Alternatives to laboratory animals : ATLA

Year:

2002

Language:

english

File:

PDF, 92 KB

english, 2002

16

Interactive effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and retinoids on proliferation and differentiation in cultured human keratinocytes: quantification of cross-linked envelope formation

Jos A. M. Berkers, Ine Hassing, Bert Spenkelink, Abraham Brouwer, Bas J. Blaauboer

Journal:

Archives of Toxicology

Year:

1995

Language:

english

File:

PDF, 1.14 MB

english, 1995

17

Proceedings of the sixteenth international workshop on in vitro toxicology

Bas J. Blaauboer, Maria Laura Scarino, Jan van der Valk

Journal:

Toxicology in Vitro

Year:

2011

Language:

english

File:

PDF, 140 KB

english, 2011

18

On the incorporation of chemical-specific information in risk assessment

Harvey J. Clewell III, Melvin E. Andersen, Bas J. Blaauboer

Journal:

Toxicology Letters

Year:

2008

Language:

english

File:

PDF, 591 KB

english, 2008

19

CASES OCCURRING IN THE PRACTICE OF THE PHYSICIANS OF THE LONDON HOSPITAL.

Vinken, Mathieu, Scarino, Maria Laura, Roggen, Erwin, Blaauboer, Bas J.

Journal:

Year:

1842

Language:

english

File:

PDF, 470 KB

english, 1842

20

Supplement 2 || Joint Reports 13th Meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): Alternative Testing Methodologies and Conceptual Issues

Bas J. Blaauboer, Michael Balls, Martin Barratt, Silvia Casati, Sandra Coecke, Mostafa K. Mohamed, Jack Moore, David Rall, Kirk R. Smith, Raymond Tennant, B. A. Schwetz, William S. Stokes and Maged Yo

Journal:

Environmental Health Perspectives

Year:

1998

Language:

english

File:

PDF, 1006 KB

english, 1998

21

Solid Phase Microextraction as a Tool To Determine Membrane/Water Partition Coefficients and Bioavailable Concentrations in in Vitro Systems

Vaes, Wouter H. J., Urrestarazu Ramos, Eñaut, Hamwijk, Casper, van Holsteijn, Ineke, Blaauboer, Bas J., Seinen, Willem, Verhaar, Henk J. M., Hermens, Joop L. M.

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 114 KB

english, 1997

22

Regulatory acceptance and use of the Extended One Generation Reproductive Toxicity Study within Europe

Schiffelers, Marie-Jeanne W.A., Blaauboer, Bas J., Bakker, Wieger E., Hendriksen, Coenraad F.M., Krul, Cyrille

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 606 KB

english, 2015

23

Effects of 1,2-dibromoethane on isolated hepatocytes: Functional alterations and induction of lipid peroxidation

Van Iersel, Arthur A. J., Van Holsteijn, Ineke, Blaauboer, Bas J.

Journal:

Year:

1988

Language:

english

File:

PDF, 761 KB

english, 1988

24

The Necessity of Biokinetic Information in the Interpretation of In Vitro Toxicity Data

Blaauboer, Bas J.

Journal:

Alternatives to laboratory animals : ATLA

Year:

2002

File:

PDF, 92 KB

2002

25

Cytochrome P450 induction and metabolism of alkoxyresorufins, ethylmorphine and testosterone in cultured hepatocytes from goats, sheep and cattle

Gerben A.E. van't Klooster, Bas J. Blaauboer, Jan Noordhoek, Adelbert S.J.P.A.M. van Miert

Journal:

Biochemical Pharmacology

Year:

1993

Language:

english

File:

PDF, 1.05 MB

english, 1993

26

Hepatic cytochrome P450 induction in goats: Effects of model inducers on the metabolism of alkoxyresorufins, testosterone and ethylmorphine, and on apoprotein and mRNA levels

Gerben A.E. Van't Klooster, G.J.M.Jean Horbach, Masahiro Natsuhori, Bas J. Blaauboer, Jan Noordhoek, Adelbert S.J.P.A.M. Van Miert

Journal:

Biochemical Pharmacology

Year:

1993

Language:

english

File:

PDF, 1.34 MB

english, 1993

27

Quantitative in vitro to in vivo extrapolation (QIVIVE): An essential element for in vitro-based risk assessment

Yoon, Miyoung, Blaauboer, Bas J., Clewell, Harvey J.

Journal:

Year:

2015

Language:

english

File:

PDF, 141 KB

english, 2015

28

In vitro testing of basal cytotoxicity: Establishment of an adverse outcome pathway from chemical insult to cell death

Vinken, Mathieu, Blaauboer, Bas J.

Journal:

Toxicology in Vitro

Year:

2017

Language:

english

File:

PDF, 595 KB

english, 2017

29

Differences in the effects of model inducers of cytochrome P450 on the biotransformation of scoparone in rat and hamster liver

Wim C. Mennes, Niels B. Lucas Luijckx, Heleen M. Wortelboer, Jan Noordhoek, Bas J. Blaauboer

Journal:

Archives of Toxicology

Year:

1993

Language:

english

File:

PDF, 619 KB

english, 1993

30

Evaluation of research activities and research needs to increase the impact and applicability of alternative testing strategies in risk assessment practice

Ans Punt, Marie-Jeanne W.A. Schiffelers, G. Jean Horbach, Johannes J.M. van de Sandt, Geny M.M. Groothuis, Ivonne M.C.M. Rietjens, Bas J. Blaauboer

Journal:

Regulatory Toxicology and Pharmacology

Year:

2011

Language:

english

File:

PDF, 499 KB

english, 2011

31

Excessive levels of diverse phytoestrogens can modulate steroidogenesis and cell migration of KGN human granulosa-derived tumor cells

Solak, Kamila A., Wijnolts, Fiona M.J., Nijmeijer, Sandra M., Blaauboer, Bas J., van den Berg, Martin, van Duursen, Majorie B.M.

Journal:

Toxicology Reports

Year:

2014

Language:

english

File:

PDF, 1.87 MB

english, 2014

32

Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing

Hamm, Jon, Sullivan, Kristie, Clippinger, Amy J., Strickland, Judy, Bell, Shannon, Bhhatarai, Barun, Blaauboer, Bas, Casey, Warren, Dorman, David, Forsby, Anna, Garcia-Reyero, Natàlia, Gehen, Sean, Gr

Journal:

Toxicology in Vitro

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

33

Transport of Chlorpromazine in the Caco-2 Cell Permeability Assay: A Kinetic Study

Broeders, Jessica J. W., van Eijkeren, Jan C. H., Blaauboer, Bas J., Hermens, Joop L. M.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 781 KB

english, 2012

34

In vitro biokinetics of chlorpromazine and the influence of different dose metrics on effect concentrations for cytotoxicity in Balb/c 3T3, Caco-2 and HepaRG cell cultures

Broeders, Jessica J.W., Blaauboer, Bas J., Hermens, Joop L.M.

Journal:

Toxicology in Vitro

Year:

2013

Language:

english

File:

PDF, 551 KB

english, 2013

35

Scientifically unfounded precaution drives European Commission’s recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles

Dietrich, Daniel R., Aulock, Sonja von, Marquardt, Hans, Blaauboer, Bas, Dekant, Wolfgang, Kehrer, James, Hengstler, Jan, Collier, Abby, Gori, Gio Batta, Pelkonen, Olavi, Lang, Florian, Barile, Frank

Journal:

Chemico-Biological Interactions

Year:

2013

Language:

english

File:

PDF, 264 KB

english, 2013

36

Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals

Murk, AlberTinka J., Rijntjes, Eddy, Blaauboer, Bas J., Clewell, Rebecca, Crofton, Kevin M., Dingemans, Milou M.L., David Furlow, J., Kavlock, Robert, Köhrle, Josef, Opitz, Robert, Traas, Theo, Visser

Journal:

Toxicology in Vitro

Year:

2013

Language:

english

File:

PDF, 921 KB

english, 2013

37

Quantifying Processes Determining the Free Concentration of Phenanthrene in Basal Cytotoxicity Assays

Kramer, Nynke I., Krismartina, Mirna, Rico-Rico, Ángeles, Blaauboer, Bas J., Hermens, Joop L. M.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 1.76 MB

english, 2012

38

An alkaline phosphatase transport mechanism in the pathogenesis of Alzheimer’s disease and neurodegeneration

Pike, Adrianne F., Kramer, Nynke I., Blaauboer, Bas J., Seinen, Willem, Brands, Ruud

Journal:

Chemico-Biological Interactions

Year:

2015

Language:

english

File:

PDF, 979 KB

english, 2015

39

Eleventh International Workshop on In Vitro Toxicology: 25–28 October 2000, Pueblo Acantilado, El Campello (Alicante), Spain

Jan van der Valk, Annalaura Stammati, Horst Spielmann, Bas Blaauboer

Journal:

Toxicology in Vitro

Year:

2001

Language:

english

File:

PDF, 57 KB

english, 2001

40

Twelfth International Workshop on In Vitro Toxicology: 16–19 October 2002

Emanuela Testai, Jan van der Valk, Bob Combes, Bas Blaauboer

Journal:

Toxicology in Vitro

Year:

2003

Language:

english

File:

PDF, 70 KB

english, 2003

41

Naringenin (NAR) and 8-prenylnaringenin (8-PN) reduce the developmental competence of porcine oocytes in vitro

Solak, Kamila A., Santos, Regiane R., van den Berg, Martin, Blaauboer, Bas J., Roelen, Bernard A.J., van Duursen, Majorie B.M.

Journal:

Reproductive Toxicology

Year:

2014

Language:

english

File:

PDF, 1.24 MB

english, 2014

42

Life, death, and the RB gene

Solak, Kamila A., Santos, Regiane R., van den Berg, Martin, Blaauboer, Bas J., Roelen, Bernard A.J., van Duursen, Majorie B.M.

Journal:

Year:

1992

Language:

english

File:

PDF, 181 KB

english, 1992

43

Trisk: European advanced risk assessors accredited training programme for highly qualified toxicology experts

Corrado L. Galli, Helen Hakansson, Shirley Trice, Bas J. Blaauboer, Regine Kahl, Marco Gerevini

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 41 KB

english, 2009

44

Evaluation of simple in vitro to in vivo extrapolation approaches for environmental compounds

Yoon, Miyoung, Efremenko, Alina, Blaauboer, Bas J., Clewell, Harvey J.

Journal:

Toxicology in Vitro

Year:

2014

Language:

english

File:

PDF, 534 KB

english, 2014

45

The long and winding road of progress in the use of in vitro data for risk assessment purposes: From “carnation test” to integrated testing strategies

Blaauboer, Bas J.

Journal:

Year:

2015

Language:

english

File:

PDF, 438 KB

english, 2015

46

Scientifically unfounded precaution drives European Commission’s recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles

Dietrich, Daniel R., Aulock, Sonja von, Marquardt, Hans, Blaauboer, Bas J., Dekant, Wolfgang, Kehrer, James, Hengstler, Jan, Collier, Abby, Gori, Gio Batta, Pelkonen, Olavi, Lang, Florian, Nijkamp, Fr

Journal:

Toxicology in Vitro

Year:

2013

Language:

english

File:

PDF, 236 KB

english, 2013

47

Towards toxicity assessment without animals

Heinonen, Tuula, Tähti, Hanna, Vähäkangas, Kirsi, Blaauboer, Bas J.

Journal:

Toxicology in Vitro

Year:

2013

Language:

english

File:

PDF, 181 KB

english, 2013

48

Biokinetics in repeated-dosing in vitro drug toxicity studies

Kramer, Nynke I., Di Consiglio, Emma, Blaauboer, Bas J., Testai, Emanuela

Journal:

Toxicology in Vitro

Year:

2015

Language:

english

File:

PDF, 382 KB

english, 2015

49

The Influence of In Vitro Assay Setup on the Apparent Cytotoxic Potency of Benzalkonium Chlorides

Groothuis, Floris A., Timmer, Niels, Opsahl, Eystein, Nicol, Beate, Droge, Steven T.J., Blaauboer, Bas J., Kramer, Nynke Irene

Journal:

Chemical Research in Toxicology

Year:

2019

Language:

english

File:

PDF, 690 KB

english, 2019

50

Blood-Brain Barrier In Vitro Models and Their Application in Toxicology: The Report and Recommendations of ECVAM Workshop 49 ,

Prieto, Pilar, Blaauboer, Bas J., de Boer, Albertus Gerrit, Boveri, Monica, Cecchelli, Romeo, Clemedson, Cecilia, Coecke, Sandra, Forsby, Anna, Galla, Hans-Joachim, Garberg, Per, Greenwood, John, Pric

Journal:

Alternatives to laboratory animals : ATLA

Year:

2004

Language:

english

File:

PDF, 149 KB

english, 2004

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